entity Updated 2026-08-24 Tags: Drug, Healthcare, Neuroscience, Sleep

Ovoperextone

Ovoperextone is the Takeda Pharmaceutical / 武田制药 drug named in Wake-up haul: an Ozempic moment for the brain as the first concrete orexin agonist case. The source describes it as approved by the FDA to treat narcolepsy.

The page should keep that claim source-scoped to this episode unless later sources add regulatory or clinical detail. In the episode, ovoperextone matters because it turns orexin from a discovery story into a drug-market question, while the broader hopes for depression, ADHD, and addiction remain speculative.

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